Tropical - parameter estimation and simulation of reaction-diffusion models based on spatio-temporal microscopy images

نویسندگان

  • Markus Ulrich
  • Constantin Kappel
  • Joël Beaudouin
  • Stefan Hezel
  • Jochen Ulrich
  • Roland Eils
چکیده

UNLABELLED Tropical is a software for simulation and parameter estimation of reaction-diffusion models. Based on spatio-temporal microscopy images, Tropical estimates reaction and diffusion coefficients for user-defined models. Tropical allows the investigation of systems with an inhomogeneous distribution of molecules, making it well suited for quantitative analyses of microscopy experiments such as fluorescence recovery after photobleaching (FRAP). AVAILABILITY Tropical is available free of charge for academic use at http://www.dkfz.de/tbi/projects/modellingAndSimulationOfCelluarSystems/tropical.jsp after signing a material transfer agreement.

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عنوان ژورنال:
  • Bioinformatics

دوره 22 21  شماره 

صفحات  -

تاریخ انتشار 2006